KINETIC MODELING OF DISSOLUTION PROFILES OF NONIONIC SURFACTANT RIFAMPICIN NIOSOMES
نویسندگان
چکیده
منابع مشابه
Formulation and Characterization of Drug Loaded Nonionic Surfactant Vesicles (Niosomes) for Oral Bioavailability Enhancement
Nonionic surfactant vesicles (niosomes) were formulated with an aim of enhancing the oral bioavailability of tenofovir disoproxil fumarate (TDF), an anti-HIV drug. Niosomes were formulated by conventional thin film hydration technique with different molar ratios of surfactant, cholesterol, and dicetyl phosphate. The formulated niosomes were found spherical in shape, ranging from 2.95 μm to 10.9...
متن کاملModeling and comparison of dissolution profiles.
Over recent years, drug release/dissolution from solid pharmaceutical dosage forms has been the subject of intense and profitable scientific developments. Whenever a new solid dosage form is developed or produced, it is necessary to ensure that drug dissolution occurs in an appropriate manner. The pharmaceutical industry and the registration authorities do focus, nowadays, on drug dissolution s...
متن کاملModeling and comparison of dissolution profiles pdf
European Journal of Pharmaceutical Sciences 13 2001 123133 www.elsevier.nllocateejps. Modeling and comparison of dissolution profiles.To compare dissolution profiles between two drug products model dependent curve fitting, statistic analysis and model independent methods can be used. To compare dissolution profiles between two drug products model dependent curve fitting, statistic analysis and ...
متن کاملStudy of the Cloud Point of Nonionic Surfactant and Nonionic-cationic Surfactant Mixture: Effect of Electrolytes
Clouding phenomenon generally occurs with nonionic surfactants when the temperature of the system is raised to a certain value. This critical temperature is termed the cloud point (CP). The aqueous solutions of nonionic surfactants show complex phase behaviour including liquid-liquid phase separation at this temperature. The cloud point of aqueous surfactant solutions is influenced by the prese...
متن کاملFormulation and in-vitro evaluation of Rifampicin-Loaded Niosomes
To prepare niosomes containing rifampicin were prepared using various nonionic surfactants of sorbitan ester class and cholesterol in 50:60 (1:1.2) percent mol fraction ratios for sustain release. To improve the dissolution rate of noisome are prepare handshaking method using Surfactants and cholesterol (150 μmol) in 50:60 (1:1.2) percent mol fraction ratio. The percent of drug estimated to be ...
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ژورنال
عنوان ژورنال: Journal of Comprehensive Pharmacy
سال: 2016
ISSN: 2349-5669
DOI: 10.37483/jcp.2016.3501